What is CovaCoat®?
CovaCoat® is a proprietary photochemical process that permanently alters the surface of a variety of medical devices, to improve functionality and performance. Using our validated CovaCoat® technology platform, we collaborate with customers to incorporate or customize the technology to develop unique medical devices that are cost-effective and allow for strategic marketing advantages for their product offerings.
CovaCoat® may be customized to provide medical devices specific properties:
· Controlled drug delivery
· ID/OD coating
The CovaCoat® process works best with polymer-based materials but can be applied to virtually any medical device or other surface material. Using USP grade material and an ISO compliant quality system, the CovaCoat® process has been scaled for commercial production of many FDA, Health Canada, CFDA approved products.
Features and Benefits:
Durable: Covalently linked surface coating withstands very high shearing and abrasion forces
Highly tunable: Adaptable to varying geometries, devices and materials (pre or post processing), ID and OD coating
Multifunctional: Allowing for multiple surface properties, functionalities and controlled delivery of APIs, all in one coating formulation
Customizable: Providing unique market differentiating solutions for every customer
Patented: A unique (or differentiating) approach to surface modification
Controlled delivery: Including but not limited to antimicrobials, antibiotics, peptides and anti‐inflammatories
Cost Effective: A flexible business model allows for creative structures that are mutually beneficial
A Quicker Path to Market: Process has been scaled commercially at our in-house manufacturing facility, as well as transferred to third parties.
Commercially Proven: Multiple applications in market with clinical validation
Our proprietary photo-polymerization, “grafting from” process results in a permanent covalent bond between the coating and medical device surface.
This unique process uses an in-situ reaction that enables grafting sites to slightly penetrate the surface of the medical device forming a continuum rather than a discreet coating layer, the latter of which is more susceptible to delamination and particulate formation.
Low Particulate, Lubricious Coating: Centaur™
Centaur™ low particulate, lubricious coating is designed to improve the safety and functionality of intravascular medical devices, such as vascular access catheters, where the presence of unwanted particulate can cause significant patient complications. In a third party in vitro simulated vascular insertion study designed to measure the levels of particulate, Covalon’s Centaur™ coating resulted in significantly lower levels for all particulate sizes relative to the uncoated control. This contrasts with other industry leading coatings that generate nearly twice as many particles as the same catheter without a coating. Covalon’s Centaur™ coating technology specifically targets and is ideally suited for a growing segment of the medical coatings market focused on minimizing coating degradation without compromising lubricity.
Infection Prevention Coatings
Using the CovaCoat® process, our infection prevention coatings are not restricted to one specific antimicrobial. We leverage various antimicrobials, antibiotics and combinations thereof, which are incorporated into the coating and tuned accordingly, to achieve the target elution profile and efficacy of the device. The Covalon development team works closely with customers to understand the best infection prevention solution for their device and market, resulting in a unique, market differentiating coating unlike any of their competitors.
Controlled Drug Delivery Coatings
The CovaCoat® Process can be combined with various active pharmaceutical ingredients (APIs), including, but not limited to, antimicrobials, anti-inflammatories, pain relief compounds, antibiotics. Based on the target efficacy, the CovaCoat™ process is modulated to provide the appropriate elution for a target application.
Our specialists employ the latest science methodologies to create customized solutions for our clients. We work with major pharmaceutical companies to extend the life-time of their patented proprietary compounds. For more information about our customized coating solutions, please contact our specialists.